Objective To a nalyz e the etiology,clinical characteristics and the selection of anti-seizure medications(ASM)of elderly individuals with epilepsy(EIWE).Methods A total of 313 EIWE,who visited the Department of Neurology of General Hospital of Ningxia Medical University from June 2020 to April 2023 were collected.The etiology of epilepsy,electroencephalogram(EEG)results,selection of ASM were retrospectively analyzed,and the composition of the etiology and the ASM application were summarized.Results A total of 205(65.5%)cases had clear causes,with stroke being the most common cause(54.1%,111/205 cases),followed by brain trauma(29.8%,61/205 cases).The EIWE in 65-＜75 years old group were mainly due to unknown causes(P＜0.05),and the others in 75-＜85 years old group were mainly due to stroke(P＜0.05).There was no statistically significant difference in the distribution of causes among the≥85 years old group(P>0.05).199 cases underwent EEG examination,of which 165(82.9%)cases had epileptiform discharges and 34(17.1%)cases were normal(P＜0.05).131 individuals'brain MRI and(or)CT showed lesions,of which 86(65.6%)cases involved the cortex.There were statistically significant differences in epileptiform discharge,cranial MRI and/or CT lesions among different age groups(P all<0.05).The main accompanying disease for EIWE was hypertension.295(94.2%)individuals received ASM treatment,including 185(62.7%)cases with single ASM,consisting of 111(60.0%)cases with new ASM and 74(40.0%)cases with traditional ASM;110(37.3%)cases were treated with two and more kinds of ASM;18(5.8%)individuals did not use ASM.Conclusion The main cause of elderly epilepsy is stroke,with a high positive rate of EEG.The main accompanying disease in elderly epilepsy patients is hypertension,and the treatment of ASM mainly relies on new monotherapy.
关键词
老年癫痫/病因/抗癫痫发作药物
Key words
elderly individuals with epilepsy/etiology/anti-seizure medications
维普
万方数据