Clinical effect analysis of different non-surgical therapeutic regimen in adenomyosis
Objective To investigate the clinical effect of different non-surgical therapeutic regimenin adenomyosis.Methods The clinical data of 130 patients with adenomyosis treated with non-operation were retrospectively analyzed.According to the attending physician and the therapeutic regimen choosed by patients,they were divided into group A(LNG-IUS group,50 cases),group B(GnRH-a+LNG-IUS group,50 cases)and group C(dienogest group,30 cases).The changes of uterine volume,menstrual vol-ume,relief of dysmenorrhea symptoms,incidence of adverse reactions and recurrence rate were observed before and after treatment in each group to evaluate the clinical therapeutic effect.Results The uterine volume of group B was lower than that of group A and group A was lower than that of group C at all time points after treatment,and the difference was statistically significant(P＜0.05).The VAS score of group C was lower than that of group A at all time points after treatment,and the difference was statistically significant(P＜0.05).The VAS score and PBAC score of group B were lower than those of group A at 3 and 6 months after treatment,and the difference was statisti-cally significant(P＜0.05).The PBAC score of group C was lower than that of group B at 3 and 6 months after treatment,and the differ-ence was statistically significant(P＜0.05).PBAC score in group C was lower than that in group A at 12 months and 24 months after treatment,and the difference was statistically significant(P＜0.05).There was no significant difference between group C and group A in the occurrence of irregular bleeding(P＞0.05).Conclusion Although all three groups of treatment can alleviate clinical symptoms,the GnRH-a+LNG-IUS group is the most effectiveve.
万方数据
维普
