首页|左室压力应变环技术评估瓣膜功能正常的二叶式主动脉瓣患者亚临床左室心肌功能

左室压力应变环技术评估瓣膜功能正常的二叶式主动脉瓣患者亚临床左室心肌功能

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目的 探讨超声心动图压力应变环技术(PSL)技术评价瓣膜功能正常的二叶式主动脉瓣(BAV)患者亚临床左室心肌功能.方法 收集二叶式主动脉瓣患者作为病例组(BAV组,n =40),另选取主动脉瓣三叶瓣(TAV)的健康志愿者为对照组(TAV组,n =40).各组获取2D-TTE参数,包括LVDd、LVDs、IVSd、LVpWd、MpA、LAD、LVEF,计算E/A、E/e'值.应用 2D-STI技术获取左室GLS,应用PSL技术获取心肌做功参数,包括GWI、GCW、GWW及GWE.计算升主动脉AosI、Aortic Strain和AODSI.比较2 组之间的差异,分析BAV组左室心肌做功参数与升主动脉Aortic Stain、AosI、AODSI参数的相关性.结果 2D-TTE参数:BAV组较对照组E/A和E/e'参数均有所下降(P<0.05);BAV组较对照组GLS(绝对值)、GWI、GCW和GWE下降,GWW升高,2 组比较差异有统计学意义(P<0.05);BAV组Aortic Stain、AODSI值较TAV组下降,AosI值较TAV组增加,2 组比较差异有统计学意义(P<0.05).BAV 组中 GWI、GCW 与 Aortic Stain、AODSI 呈正相关(r 分别为 0.716、0.395、0.265、0.359,P<0.05).结论 PSL技术能够早期检出瓣膜功能正常的BAV患者亚临床左室心肌损害;瓣膜功能正常的BAV患者早期亚临床左室心肌损害可能与升主动脉结构或功能有关.
Evaluation of subclinical left ventricular myocardial function by the left ventricular pressure-strain loop technique in patients with bicuspid aortic valves with normal valve function
Objective To explore the evaluation of subclinical left ventricular myocardial function in BAV patients with normal valve function by using the echocardiographic PSL technology.Methods 40 patients with bicuspid aortic valves were collected as the BAV group and 40 healthy volunteers with trileaflet aortic valves were selected as the TAV group.2D-TTE parameters including LVDd,LVDs,IVSd,LVPWd,MPA,LAD and LVEF were obtained in each group,and E/A and E/e'values were calculated.2D-STI technique was ap-plied to obtain LV GLS.The PSL technique was applied to obtain myocardial work parameters,including GWI,GCW,GWW and GWE.As-cending aortic AosI,Aortic Strain and AODSI were calculated.The difference between the two groups was compared.The correlation be-tween the LV myocardial work parameters in the BAV group and the Aortic Stain,AosI and AODSI parameters in the ascending aortic were analyzed.Results 2D-TTE parameters:E/A and E/e'parameters decreased in the BAV group compared with the control group,and the differences were statistically significant(P<0.05).Compared with the TAV group,GLS(absolute value),GWI,GCW and GWE de-creased and GWW increased in the BAV group(P<0.05).Compared with the TAV group,Aortic Stain and AODSI values decreased in BAV group and AosI values increased(P<0.05).Correlation analysis showed that there was a significant positive correlation between GWI,GCW and Aortic Stain,AODSI in the BAV group(r =0.716,0.395,0.265,0.359,P<0.05).Conclusion PSL technology can ear-ly detect subclinical LV myocardial damage in BAV patients with normal valve function at an early stage.Early subclinical LV myocardial damage in BAV patients with normal valve function may be related to the structure or function of the ascending aorta.

Bicuspid aortic valveLeft ventricular pressure-strain ring techniqueMyocardial workAortic valve

吴楠、王栎茗、王莉莉、纳丽莎

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宁夏医科大学,宁夏 银川 750004

宁夏医科大学总医院心脏中心,宁夏 银川 750004

二叶式主动脉瓣 左室压力应变环技术 心肌做功 主动脉瓣

宁夏回族自治区自然科学基金

2023AAC03635

2024

宁夏医学杂志
中华医学会宁夏分会

宁夏医学杂志

影响因子:0.706
ISSN:1001-5949
年,卷(期):2024.46(4)
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