Research on the correlation between 25-(OH)vitamin D level detection and pediatric ADHD scale scores
Objective To explore the correlation between 25-(OH)vitamin D level detection and pediatric attention deficit hyperactivity disorder(ADHD)scale scores,and to find a model to predict ADHD severity.Methods 40 children with ADHD were se-lected as the study subject and 40 healthy children during the same period were selected as the normal control group.According to the Canadian Association of Pediatrics,children with 25-(OH)D level below 30 ng/ml were selected as the abnormal group(n =16),and children with 25-(OH)D level above 30 ng/ml were selected as the normal group(n =24).The 25-(OH)D level of ADHD group and the control group were compared.The 25-(OH)D levels in children with ADHD of different severity were compared.The differ-ence in the scores of the Conners Parent Questionnaire for ADHD children with different 25-(OH)D levels was detected.Pearson cor-relation was used to analyze the correlation between 25-(OH)D index and Conners parent questionnaire score,and the ROC curve was used to analyze the efficacy of 25-(OH)D in predicting ADHD severity.Results The level of 25-(OH)D in the ADHD group was significantly smaller than that in the control group(P<0.05).According to the Conners Parent Questionnaire,the scores of 25-(OH)D abnormalities were significantly higher than those in the normal group(P<0.05),and there were no significant statistical differences between other groups(P>0.05).There was a negative correlation between the total score of the Conners Parent Questionnaire score and the serum 25-(OH)D level(P<0.05).The AUC for predicting the severity of ADHD by25-(OH)D levels was0.728,with95%CI of 0.608-0.781.Conclusion There is a negative correlation between the total score of Conners Parent Questionnaire and serum 25-(OH)D level,and the 25-(OH)D detection can improve the diagnostic efficiency of ADHD and provide a reference for judging the severity of the disease.
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