首页|呼吸康复阀在慢阻肺气道黏液高分泌表型中的疗效观察

呼吸康复阀在慢阻肺气道黏液高分泌表型中的疗效观察

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目的 比较呼吸康复阀与胸部物理训练在稳定期慢阻肺患者肺康复排痰治疗中的临床效果.方法 将58例稳定期慢阻肺患者随机分组,试验组(32例)给予呼吸康复阀训练,对照组(26例)行主动咳嗽训练,各自共进行为期3个月的排痰干预训练,对比两组患者干预前后的肺功能指标、咳嗽和咳痰症状以及生活质量等变化.结果 与对照组相比,试验组肺功能指标FEV1、FVC及FEV1/FVC%较训练前显著改善(P<0.05).干预训练前、后比较,两组在咳嗽咳痰症状、mMRC等级、CAT评分、CCQ评分、SGRQ评分、Borg评分及6MWD等方面均有变化,且试验组mMRC等级、CAT评分及6MWD改善程度均显著高于对照组(P<0.05).结论 慢阻肺的基本治疗,辅以肺康复排痰训练能够改善稳定期慢阻肺患者的咳嗽咳痰症状,呼吸康复阀训练能够改善稳定期慢阻肺患者的部分肺功能指标、生活质量及运动耐力,值得进一步研究及推广.
Efficacy of a Respiratory Rehabilitation Valve in Chronic Obstructive Pulmonary Disease with Airway Mucus Hypersecretion Phenotype
Objective To compare the clinical effects of a respiratory rehabilitation valve and chest physical training on pulmo-nary rehabilitation and expectoration in patients with stable chronic obstructive pulmonary disease(COPD).Methods Fifty-eight pa-tients with stable COPD were randomly divided into two groups.The experimental group(n=32)received respiratory rehabilitation valve training,while the control group(n=26)underwent active cough training.Both groups received expectoration intervention train-ing for three months.The changes in lung function indices,cough and expectoration symptoms,and quality of life were compared be-tween the two groups before and after the intervention.Results The experimental group showed significant improvements in lung function indices(FEV1,FVC,and FEV1/FVC%)compared to the control group post-training(P<0.05).Improvements were also observed in symptoms of cough and expectoration,mMRC,COPD Assessment Test(CAT),Clinical COPD Questionnaire(CCQ),St George's Respiratory Questionnaire(SGRQ),Borg Dyspnea Score(Borg),and 6-minute walking distance(6MWD).The improvements in mMRC grade,CAT score,and 6MWD were significantly higher in the experimental group than in the control group(P<0.05).Conclusion Basic treatment of COPD,supplemented by lung rehabilitation and expectoration training,can improve the symptoms of cough and expectoration in patients with stable COPD.Respiratory rehabilitation valve training can enhance some pulmonary function in-dices,quality of life,and exercise endurance in patients with stable COPD,warranting further study and promotion.

Stable chronic obstructive pulmonary diseaserespiratory rehabilitation valvepulmonary rehabilitation

王金霞、王玉玲、王蓓、李进霞、徐淑萍、张雅囡、陈娟

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宁夏医科大学,宁夏银川 750004

宁夏医科大学总医院呼吸与危重症医学科,宁夏银川 750004

宁夏吴忠市人民医院呼吸与危重症医学科,宁夏吴忠 751100

稳定期慢性阻塞性肺疾病 呼吸康复阀 肺康复

国家自然科学基金

82060013

2024

宁夏医学杂志
中华医学会宁夏分会

宁夏医学杂志

影响因子:0.706
ISSN:1001-5949
年,卷(期):2024.46(5)
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