Diagnosis value of ultrasound-guided cytological and histological biopsy in axillary lymph nodes metastasis of breast cancer
Objective To compare the diagnostic value of ultrasonography-guided fine needle aspiration(FNA)and core needle biopsy(CNB)in axillary lymph node metastasis of primary breast cancer.Methods 172 breast cancer patients with suspected axillary lymph node abnormalities diagnosed by conventional ultrasound was conducted.Among them,80 cases were detected by FNA and 92 cases were detected by CNB.The accuracy,sensitivity,specificity and incidence of complications of FNA and CNB in detecting axillary lymph node metastasis were evaluated with postoperative pathological results as the gold standard.Results A total of 172 patients with breast cancer were included.According to the postoperative pathological results,132 of them had metastasis and 40 had no metastasis.Compared with the gold standard,the accuracy,sensitivity and specificity of FNA detection were 86.25％,85.71％and 88.24％,respec-tively.The accuracy,sensitivity and specificity of CNB detection were 95.65％,94.20％and 100％,respectively.The accuracy of CNB detection was significantly higher than that of FNA(P＜0.05).There was no significant difference in sensitivity and specificity between CNB and FNA(P＞0.05).There was no significant difference in the incidence of puncture complications such as bleeding,pain,infec-tion and pneumothorax between CNB and FNA(P＞0.05).Conclusion FNA and CNB have high diagnostic value in the diagnosis of lymph node metastasis of breast cancer.Compared with FNA detection,CNB has higher accuracy and no increase in the incidence of com-plications.
Breast cancerLymph node metastasisUltrasoundCytologyHistologyBiopsy
NETL
NSTL
万方数据
