Effects of low-dose high viscosity bone cement percutaneous vertebroplasty on the elderly patients with osteoporotic thoracolumbar fracture
Objective To explore the effects of low-dose high viscosity bone cement percutaneous vertebroplasty(PVP)on the recovery of vertebral height,vertebral function,pain degree and bone cement leakage in elderly patients with osteoporotic thoracolum-bar fracture(OTF).Methods 104 elderly patients with OTF were collected and randomly divided into low-dose group and high-dose group,52 cases in each group.PVP was performed in both groups.The low-dose group was filled with low-dose(≤3 mL)high-vis-cosity bone cement,and the high-dose group was filled with high-dose(＞3 mL)high-viscosity bone cement.The leakage rate of bone cement,the recovery of vertebral height before and after surgery[Cobb Angle,height of injured anterior vertebra(AVH)],vertebral function[oswestry disability index(ODI)],and pain degree[pain numerical score(NRS)]were compared between the two groups.Results The total leakage rate of bone cement in low-dose group was significantly lower than that in high-dose group(P＜0.05).After 3 months of operation,the Cobb Angle in the low-dose group was lower than that in the high-dose group,and the AVH was high-er than that in the high-dose group(P＜0.05).After 3 months of operation,ODI and NRS scores in low-dose group were lower than those in high-dose group(P＜0.05).Conclusion The application of low-dose and high-viscosity bone cement in PVP treatment of elderly patients with OTF can reduce the risk of bone cement leakage,promote the recovery of AVH and Cobb Angle of injured vertebrae,improve the function of vertebrae,and alleviate pain.
Osteoporotic thoracolumbar fracturePercutaneous vertebroplastyHigh viscosity bone cementLow-doseHigh-dose
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