首页|纤维支气管镜下灌洗吸引技术在合并肺部感染老年患者急诊全麻手术中的应用

纤维支气管镜下灌洗吸引技术在合并肺部感染老年患者急诊全麻手术中的应用

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目的 分析评价纤维支气管镜下灌洗吸引技术在合并肺部感染老年患者急诊全麻手术中应用的效果.方法 选择进行急诊手术且合并肺部感染的老年患者60例,将其随机分为A组和B组,每组30例.在全麻气管插管后A组采用普通吸痰管吸引,B组采用纤维支气管镜灌洗吸引技术.分别记录2组患者术前(T0)、吸引后30 min(T1)、60 min(T2)、90 min(T3)及手术结束后1 h(T4)各时间点血氧饱和度(SpO2)、氧合指数(PaO2/FiO2),记录T,、T2及T3时间点呼吸力学指标(Pplat、Ppeak、Cdyn),记录手术时长、苏醒时间以及术前、术后24与48 h炎性因子指标,术前与术后24h、48 h临床肺部感染评分(CPIS)及术后48 h胸部CT结果.结果 2组患者SpO2及PaO2/FiO2在T0时间点比较差异无统计学意义(P>0.05),在T,、T2、T3及T4时间点较T0均上升,差异有统计学意义(P<0.05),且B组上升幅度明显高于A组,组间比较差异有统计学意义(P<0.05);呼吸力学方面比较,2组患者在T,、T2、T3时间点差异有统计学意义(P<0.05);2组患者苏醒时间、手术时间比较差异无统计学意义(P>0.05);2组患者炎性因子指标(PCT、TGF-β、IL-8)及CPIS评分比较,B组在术后24 h、48 h明显低于术前(P<0.05)且A、B组间比较差异有统计学意义(P<0.05).B组术后48 h胸部CT显示肺部炎症较前片明显好转的例数显著高于A组(P<0.05).结论 采用纤维支气管镜下灌洗吸引技术,在合并肺部感染的老年患者行急诊全麻手术时,可改善其肺通气和换气功能,减轻炎性反应,改善预后.
Application of fiberoptic bronchoscopic irrigation and suction technique in emergency surgery for elderly patients with lung infection undergoing general anesthesia
Objective To analyze and evaluate the effect of fiberoptic bronchoscopic irrigation and suction technique applied in emergency surgery for elderly patients with lung infection.Methods Sixty cases of elderly patients who underwent emergency surgery with combined lung infection were selected.They were randomly divided into group A and group B(n=30).After tracheal intubation un-der general anesthesia,group A was suctioned with ordinary suction tubes,and group B was suctioned with fiberoptic bronchoscopic lavage technique.Blood oxygen saturation and oxygenation index at each time point of preoperative(T0),30 minutes after suction(T,),60 mi-nutes(T2),90 minutes(T3)and one hour after the end of the operation(T4)were recorded in the two groups,respiratory mechanical indexes(Pplat,Ppeak,Cdyn)at the time points of T,,T2 and T,were recorded,and the length of the operation,the awakening time as well as the inflammatory factor indexes in the preoperative,24 and 48 hours after operation were recorded,and the inflammatory factor inde-xes in the preoperative,24 hours and 48 hours after operation were recorded,and the inflammatory factor indexes in the preoperative and 48 hours after operation were recorded.The length of surgery,awakening time,as well as preoperative,24-hour and 48-hour postoperative in-flammatory factor indexes,preoperative and postoperative 24-hour and 48-hour Clinical Pulmonary Infection Score(CPIS)and 48-hour postoperative chest CT results were recorded.Results There was no statistical difference in SpO2 and PaO2/FiO2 between the two groups at the T0 time point(P>0.05),and they increased at the T1,T2,T3 and T4 time points compared with T0,with statistical differences(P<0.05),and the increase in group B was significantly higher than that in group A(P<0.05);the differences in respiratory mechanics were significant between the two groups at the T,,T2 and T3(P<0.05).There was no statistically significant difference between the two groups when comparing the awakening time and operation time(P>0.05);the inflammatory factor indexes(PCT,TGF-β,IL-8)and CPIS scores in Group B was significantly lower than those of pre-operation at 24 and 48 hours(P<0.05)and there was significantly signifiicunt between group A and group B(P<0.05).The number of cases with significant improvement in pulmonary inflammation in group B was higher than that in group A at 48 hours postoperatively(P<0.05).Conclusion The use of fiberoptic bronchoscopic irrigation and suction technique can improve pulmonary ventilation and gas exchange function,reduces the inflammatory response,and it can improve the prognosis of elderly patients with coexisting lung infections when they undergo emergency surgery.

Fiberoptic bronchoscopic suction-irrigationLung infectionElderly patientsEmergency surgery

丁志刚、杨娟、杨舒雯、梁华

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联勤保障部队第942医院麻醉科,宁夏 银川 750004

宁夏医科大学总院心脑血管病医院呼吸内科,宁夏银川 750002

纤维支气管镜吸痰灌洗 肺部感染 老年患者 急诊手术

联勤保障部队第942医院科研项目

D942JSYW2021009

2024

宁夏医学杂志
中华医学会宁夏分会

宁夏医学杂志

影响因子:0.706
ISSN:1001-5949
年,卷(期):2024.46(6)