心肺运动试验指导下个体2型糖尿病康复治疗的临床研究
Clinical study on rehabilitation treatment of individual type 2 diabetes under the guidance of cardiopulmonary exercise test
胡晓月 1全英 1付宁红 1刘红 1韩倩倩 1贠婷琳1
作者信息
- 1. 宁夏石嘴山市第二人民医院,宁夏 石嘴山 753000
- 折叠
摘要
目的 观察2 型糖尿病(T2DM)患者经心肺运动试验(CPET)指导下行个体化运动康复训练的临床疗效及安全性.方法 将100 例T2DM患者作为研究对象,按随机数字表抽取法将其平均分为观察组和对照组,每组各50 例,对照组实行运动康复训练,观察组根据CPET结果制定个体化运动处方,观察比较2 组患者干预前和干预3 个月后的血糖、脂代谢、胰岛β细胞功能、肺功能、运动能力与肺气体交换参数变化.结果 观察组患者干预3 个月后各项血糖指标均对比干预前明显下降(P<0.05).观察组患者干预3 个月后总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、身体质量指数(BMI)对比治疗前均明显下降(P<0.05),高密度脂蛋白(HDL)对比干预前明显上升(P<0.05).观察组患者干预 3 个月后胰岛素抵抗指数(HOMA-IR)对比干预前明显下降(P<0.05),胰岛β细胞功能指数(HOMA-β)、空腹胰岛素(FINS)对比干预前明显上升(P<0.05).观察组患者干预3 个月后各项肺功能指标对比干预前均明显提高(P<0.05),除最大潮气量(VTmax)和呼吸商(RQ)外,各项运动能力与肺气体交换参数对比干预前均明显提高(P<0.05).结论 T2DM患者经CPET指导下行个体化运动康复训练的效果明显,提高了运动训练的科学性与安全性,有利于控制血糖水平,改善胰岛β细胞功能和肺功能,增加患者的体适能,调节其身体状态,预防或延缓并发症发生,对改善预后有重要的临床意义.
Abstract
Objective To observe the clinical efficacy and safety of individualized exercise rehabilitation training guided by cardiopulmonary exercise test(CPET)in patients with type 2 diabetes(T2DM).Methods 100 T2DM patients were collected and di-vided into ob serotion group and contron group,with 50 cases in each group.The patients in the control group carried out the exercise re-habilitation training and the patients in the observation group formulated individualized exercise prescriptions according to the results of CPET.The blood glucose,lipid metabolism,islet β-cell function,lung function,exercise ability and pulmonary gas exchange parameters were compared before intervention and after 3 months intervention.Results After 3 months of intervention,all blood glucose indicators in the observation group significantly decreased(P<0.05).The total cholesterol(TC),triglycerides(TG),low-density lipoprotein(LDL)and body mass index(BMI)of patients in the observation group significantly decreased(P<0.05).High density lipoprotein(HDL)was significantly higher than gefore intervention(P<0.05).The insulin resistance index(HOMA-IR)of patients in the obser-vation group significantly decreased(P<0.05).The pancreatic islet β cell function iIndex(HOMA-β)and fasting insulin(FINS)of patients in the observation group significantly increased(P<0.05).After3 months of intervention,all pulmonary functionindexes of patients in the observation group were significantly improved(P<0.05).After3 months of intervention,except for maximum tidal volume(Vtmax)and respiratory quotient(RQ),all exercise abilities and pulmonary gas exchange parameters of patients in the observation group were significantly improved(P<0.05).Conclusion The effect of individualized exercise rehabilitation training for T2DM pa-tients under the guidance of CPET is obvious,which improves the scientific and safety of exercise training and helps to control blood glu-cose level and improve islets β cell function and lung function,increasing the physical fitness of patients,regulating their physical state,preventing or delaying the occurrence of complications,and have important clinical significance for improving the prognosis.
关键词
2型糖尿病/心肺运动试验/肺功能/安全性/并发症Key words
T2DM/CPET/Lung function/Safety/complication引用本文复制引用
出版年
2024
NETL
NSTL
万方数据