Objective To investigate the differential diagnostic value of integrated magnetic resonance imaging(SyMRI)for benign and malignant breast lesions.Methods 108 patients with breast lesions were retrospectively collected and confirmed by postoper-ative pathology,routine MRI and integrated magnetic resonance imaging were performed before surgery.Among them,30 patients had be-nign lesions,78 malignant lesions.Quantitative parametric plots generated by SyMRI were generated for each lesion,including T1-weighted(T1WI),T2-weighted(T2WI),and proton density-weighted(PDWI)images,pre-and post-enhancement were measured and recorded as T1,T2,PD,R1,R2 relaxation values and standard deviation(SD),and calculate its relative rate of change(ΔT1％,ΔT2％,ΔPD％).Differences between quantitative parameters between benign and malignant lesions were compared.The receiver operat-ing characteristic curve(ROC)was used to evaluate the differential diagnostic value of each quantitative parameter value and the diag-nostic model for benign and malignant breast lesions.Results The quantitative parameters of benign lesions were higher than those of malignant lesions group(P＜0.05);the differences in T1e value,T1p,T2e value,T2p value,PDp value,ΔT1％and ΔT2％between be-nign and malignant breast lesion groups were statistically significant(P＜0.05).Multivariate logistic regression analysis showed that T1e value,T1p value,and T2e value are independent influencing factors in predicting breast cancer,and the T1e+T1p+T2e diagnostic mod-el has the best effect in differential diagnosis of benign and malignant breasts(AUC=0.902).Conclusion Integrated magnetic reso-nance imaging(syMRI)can improve the discrimination of benign and malignant breast lesions,and the quantitative parameters of benign breast lesions are higher than those of malignant lesions,and the T1e+T1p+T2e diagnostic model has the best efficacy.
Integrated magnetic resonance imagingBreast cancerDiagnosis
维普
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