Investigation of the diagnostic efficiency of the Bi-parametric MRI PI-RADS v2.1 combined with clinical and biochemical indicators for prostate cancer
Objective To investigate the effects of the PI-RADS v2.1 scoring system in the diagnosis of prostate cancer(PCa)and to analyze the scheme of its combined use with laboratory markers and its correlation with Gleason grading,providing a basis for improving the accuracy of PCa imaging diagnosis.Methods Data from 341 patients who underwent bp-MRI examinations were col-lected,and finally,63 cases of PCa including 55 cases of csPCa and 98 cases of BPH confirmed by pathology with complete clinical ima-ging data were included.The laboratory examination data and imaging data of the PCa/csPCa group were compared with those of the BPH group.Results There were statistical differences in age,PSA,PV,PSAD,and PI-RADS scores between the PCa/csPCa group and the BPH group(P＜0.05).The score showed moderate correlation with Gleason grading(r=0.681).ROC curve analysis showed that PSAD and PI-RADS scores had higher diagnostic performance for PCa and csPCa than other indicators.The diagnostic performance was further improved after combining PSAD and PI-RADS scores.Conclusion The PI-RADS v2.1 scoring system combined with clinical and bi-ochemical indicators shows good diagnostic performance in the diagnosis of PCa,which can improve diagnostic consistency and accuracy.
Prostate cancerPI-RADS v2.1Prostate-specific antigen densityBi-parametric magnetic resonance imaging
万方数据
维普
