Synthesis and Insecticidal Activity of Sulfoxaflor
[Aims] Sulfoxaflor as a novel pesticide was developed by Dow AgroSciences LLC. In order to study the insecticidal activity of sulfoxaflor, the synthetic method and insecticidal activity were explored. [Results] Sulfoxaflor was synthesized by pyrrolidine, butyraldehyde and 4-ethoxy-1,1,1- trifluorobut-3-en-2-one as starting materials, and its structure was confirmed by 'H NMR, IR. Preliminary bioassays indicated that sulfoxaflor exhibited good insecticidal activitiy against aphids. [Conclusions] Sulfoxaflor was prepared with a better synthetic route, which has certain directive significance for industrial production. Sulfoxaflor is a good fit for insecticide resistance management (IRM) programs.
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