Research progress of isoxazole compounds with fungicidal and herbicidal activities
Nitrogen-containing heterocycles,pivotal in drug development,are prevalent in both natural products and pharmaceutical compounds.Among these,isoxazole stands out as a promising candidate.Isoxazole and its derivatives serve as important organic synthons,boasting enhanced fungicidal,herbicidal,insecticidal,and other bioactive properties.This review focuses on isoxazoles exhibiting fungicidal and herbicidal activities,along with their synthesis routes reported since 2017.We comprehensively outlined the efficacy of analogues against various pathogens and weeds and briefly examines the correlation between structural variations and biological activities.This review offers insights into the advancement of isoxazole-based pesticides.
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