Design,synthesis and insecticidal activity of pyrifluquinazon analogs
[Aims]This study aims to explore new compounds with high insecticidal activity against Aphis fabae.[Methods]Taking pyrifluquinazon as the lead compound,12 analogs of it were designed and synthesized with 3-(trifluoromethyl)-1H-1,2,4-triazole,4-chloro-3-methyl-1H-pyrazole and 4-fluoronitrobenzene as the initial materials.The compounds were confirmed by 1H NMR and HRMS.[Results]The primarily test results showed that,some of the compounds displayed good insecticide activity against A.fabae at 100 mg/L.Among them,compound 13-5 had an activity of 97.2％ ,which was better than that of pyrifluquinazo(91.9％ ),while compound 13-2 had an activity over 80％ .
万方数据
维普
