棉籽中胺鲜酯和甲哌鎓残留的HPLC/MS/MS法检测及其膳食摄入风险评估
Determination of DA-6 and Mepiquat Chloride Residue in Cottonseed by HPLC-MS/MS and Dietary Intake Risk Assessment
臧娅磊 1周娟 2陈贺 2张可松 1郑先福3
作者信息
- 1. 郑州郑氏化工产品有限公司/河南省作物化控工程技术研究中心,河南 郑州 450002
- 2. 河南省农业科学院农产品质量安全研究所,河南 郑州 450002
- 3. 河南农业大学,河南 郑州 450000
- 折叠
摘要
建立了胺鲜酯和甲哌鎓在棉籽中残留的HPLC/MS/MS法检测方法,并对棉籽中胺鲜酯和甲哌鎓残留量进行了膳食摄入风险评估.胺鲜酯平均回收率分别为88%～97%,相对标准偏差分别为 6.6%～7.3%;甲哌鎓平均回收率分别为 84%～92%,相对标准偏差分别为3.6%～9.4%;棉籽中胺鲜酯和甲哌鎓的最低检测浓度均为0.01 mg/kg.按本试验设计进行施药,不同采收间隔期棉籽中胺鲜酯和甲哌鎓的残留量分别为≤0.01 mg/kg和≤0.48 mg/kg.胺鲜酯的普通人群国家估计每日摄入量是0.047 mg,占日允许摄入量的3.3%左右;甲哌鎓的国家估算每日摄入量是0.33 mg,占日允许摄入量的2.7%.认为对一般人群健康不会产生不可接受的风险.
Abstract
An analytical method for determining the residues of DA-6 and Mepiquat chloride in cottonseed was established by HPLC/MS/MS,along with a dietary intake risk assessment of cottonseed.The average recoveries of DA-6 and Mepiquat in cottonseed were shown to range from 88%to 97%and 84%to 92%,respectively,with relative standard deviations(RSD)of 6.86%to 7.3%and 3.6%to 9.4%,respectively.The limits of quantification(LOQ)were 0.01 mg/kg for cottonseed.Based on the designed application in this study,the terminal residues of DA-6 and Mepiquat chloride at different harvest interval in cottonseed were lower than 0.01mg/kg and 0.48mg/kg,respectively.The national estimated daily intake for the general population was 0.047mg for DA-6,accounting for 3.3%of the ADI.For Mepiquat chloride,it was 0.33mg,accounting for 2.7%of the ADI.It is concluded that the potential health risk induced by DA-6 and Mepiquat chloride was determined to be insignificant based on supervised residue trial data.
关键词
胺鲜酯/甲哌鎓/棉籽/残留检测/膳食摄入评估Key words
DA-6/mepiquat chloride/cottonseed/residue determination/dietary intake risk assessment引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据