Squamous cell carcinoma antigen(SCCA),a member of the ovalbumin serine protease inhibitor family,was originally used as a tumor marker for squamous cell carcinomas.In recent years,it has been found that SCCA expression is elevated in inflammatory skin diseases such as psoriasis and atopic dermatitis,and SCCA as a downstream molecule of IL-22/IL-17 and IL-4/IL-13,is involved in the occurrence and development of psoriasis and atopic dermatitis.In this paper,the research on the relationship between SCCA and psoriasis and atopic dermatitis is summarized as follows.
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