Vitiligo is a skin disease characterized by localized or generalized hypopigmentation or depigmentation of the skin mucous membrane,and can occur at any age and body parts,mostly in youth,with a global incidence of up to 0.1％～2％.Easy to diagnose but difficult to treat,traditional hormone therapy,local topical drug therapy and laser therapy can control the condition to a certain extent,but the therapeutic effect is still not satisfactory.Due to vitiligo usually has a long course of the disease,frequent recurrence,as well as some of the patients treatment resistance or adverse drug reactions,it is obviously necessary to discover new drugs to treat vitiligo.Although the pathogenesis of vitiligo has not yet been clarified,more and more attention has been paid to the intervention of vitiligo by immune mechanism.In this paper,we review the targeted immunotherapy of vitiligo in recent years to provide reference for the clinical treatment of vitiligo.
万方数据
维普
