Immune reconstitution inflammatory syndrome(IRIS)is a common complication of HIV-associated cryptococcal meningitis,which increases the mortality rate of HIV-related cryptococcal meningitis.Currently,the pathogenesis of IRIS of HIV-associated cryptococcal meningitis is not clear,which brings difficulties in the prevention and treatment of the disease.This review summarizes the latest advances in the pathogenesis,risk factors,diagnosis,and management of IRIS in HIV-associated cryptococcal meningitis.
关键词
HIV相关隐球菌脑膜炎/免疫重建综合征/发病机制/危险因素/诊断与处理
Key words
HIV-associated cryptococcal meningitis/immune reconstitution inflammatory syndrome/pathogenesis/risk factors/diagnosis and management