To analyze the etiological characteristics and epidemiological significance of yersinia pestis in Zaduo County,Qinghai Province,and to provide scientific basis for plague prevention and control surveillance in this are-a.Biochemical glycoalcohol test,virulence factor(F1+),virulence factor(VW+),pigmentation factor(Pgm+),yersinia pestis 1(Pet1+),plasmid and bacterial difference region(different)were performed in 21 strains of Yersinia pestis isolated from different Jukings in Qinghai Province from 1964 to 1989 Region-dpr)classification and other re-search.Results All the 21 strains were Tibetan plateau type,90.48％of yersinia pestis had all the four virulence factors,and all the strains carried plasmid with molecular weight of 6 × 106,45 × 106.65 × 106.DFR typing results showed that type 5 accounted for 90.48％,type 32 accounted for 4.76％and type 1b accounted for 4.76％.The Yersinia pestis in Zaduo County of Qinghai Province has the characteristics of plague pathogen in Qinghai-Tibet Plateau,and the Yersinia pestis has strong virulence.The plague surveillance and publicity should be strengthened in this area to prevent the plague from spreading to human.
维普
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