Pathogenic Characteristics and Epidemiological Significance of Yersinia Pestis in Zaduo County,Qinghai Province
To analyze the etiological characteristics and epidemiological significance of yersinia pestis in Zaduo County,Qinghai Province,and to provide scientific basis for plague prevention and control surveillance in this are-a.Biochemical glycoalcohol test,virulence factor(F1+),virulence factor(VW+),pigmentation factor(Pgm+),yersinia pestis 1(Pet1+),plasmid and bacterial difference region(different)were performed in 21 strains of Yersinia pestis isolated from different Jukings in Qinghai Province from 1964 to 1989 Region-dpr)classification and other re-search.Results All the 21 strains were Tibetan plateau type,90.48%of yersinia pestis had all the four virulence factors,and all the strains carried plasmid with molecular weight of 6 × 106,45 × 106.65 × 106.DFR typing results showed that type 5 accounted for 90.48%,type 32 accounted for 4.76%and type 1b accounted for 4.76%.The Yersinia pestis in Zaduo County of Qinghai Province has the characteristics of plague pathogen in Qinghai-Tibet Plateau,and the Yersinia pestis has strong virulence.The plague surveillance and publicity should be strengthened in this area to prevent the plague from spreading to human.