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玻璃体腔注射抗VEGF与激光治疗对老年DME患者的影响

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目的:探讨玻璃体腔注射抗血管内皮生长因子(VEGF)与激光治疗对老年糖尿病性黄斑水肿(DME)患者焦虑状况及生活质量的影响。方法:选取 2021 年 6 月 1 日~2022 年6 月1 日接受治疗的91 例DME患者,根据不同治疗方案分为对照组45 例(45 眼)和研究组 46 例(46 眼),两组实施相同的护理方式,对照组实施视网膜格栅样光凝治疗,研究组实施玻璃体腔注射抗VEGF治疗;比较两组治疗前后最佳矫正视力(BCVA)、黄斑中心凹厚度(CFT)、焦虑状况[采用状态-特质焦虑量表(STAI)]及生活质量[采用中文版低视力者生活质量量表(CLVQOL)]。结果:治疗 6 个月后,两组BCVA、CFT、STAI评分均低于治疗前(P<0。05,P<0。01),且研究组低于对照组(P<0。01);治疗 6 个月后,两组CLVQOL评分高于治疗前(P<0。05,P<0。01),且研究组高于对照组(P<0。05,P<0。01)。结论:与单纯激光治疗相比,玻璃体腔注射抗VEGF治疗对老年DME患者具有良好疗效,可有效消退黄斑水肿、提高患者视力,有助于缓解患者焦虑情绪,从而提高患者生活质量。
Comparison of the Effect of Intravitreal Injection of Anti-VEGF and Laser Therapy in Elderly Patients with Diabetic Macular Edema
Objective:To compare the effect of intravitreal injection of anti-VEGF and laser therapy in elderly patients with diabetic macular edema.Methods:A total of 91 DME patients who received treatment from June 1,2021 to June 1,2022 were selected and divided into control group(45 cases)and study group(46 cases)according to the different treatment methods.The patients in the two groups were given the same nursing care,the patients in the control group were treated with retinal grating photocoagulation therapy,and the study group was given intravitreal injection of anti-VEGF therapy.The BCVA,CFT,anxiety status and quality of life of the patients were compared be-tween the two groups before and after the treatment.Results:The scores of BCVA,CFT and STAT were lower after 6 months of treatment than those before treatment(P<0.05,P<0.01),and the scores in the study group were lower than the control group(P<0.01).After 6 months of treatment,the CLVQOL scores in both groups were higher than the scores before treatment(P<0.05,P<0.01),and the scores in the study group were higher than the control group(P<0.05,P<0.01).Conclusion:Compared with laser therapy alone,intravitreal injec-tion of anti-VEGF has a good effect on elderly DME patients,which can effectively subside macular edema,improve patients' vision,help alleviate patients' anxiety and thus improve patients' quality of life.

Diabetic macular edemaElderly patientsIntravitreal injection of anti-VEGF therapyLaser photocoagulation therapyAnxietyQuality of life

管姣姣、赵慧、李淑婷、王红

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山东大学齐鲁医院 山东济南 250012

糖尿病性黄斑水肿 老年患者 玻璃体腔注射抗VEGF治疗 激光光凝 焦虑 生活质量

2024

齐鲁护理杂志
山东省护理学会

齐鲁护理杂志

影响因子:1.452
ISSN:1006-7256
年,卷(期):2024.30(11)