Therapeutic Effects of Jupi Banxia Decoction Combined with Tongqiao Huoxue Decoction in the Treatment of Cerebral Small Vessel Disease
Objective:To explore the clinical efficacy of the combination of Jupi Banxia Decoction and Tongqiao Huoxue Decoction in the treatment of cerebral small vessel disease(CSVD),and to preliminarily ex-plore its mechanism of action.Methods:100 patients with cerebral small vessel disease were randomly divided into the control group(50 cases)and the experimental group(50 cases)using a random number table method.The control group received routine treatment,while the experimental group received additional treatment of Jupi Banxia Decoction combined with Tongqiao Huoxue Decoction on the basis of routine treatment,for a total of 3 months.The the daily living ability scale(ADL)score,C-reactive protein(CRP),D-dimer,and fibrino-gen(FIB)levels as evaluation indicators were compared.Results:After treatment,the ADL scores of both groups of patients were significantly higher than that before treatment,and the experimental group was higher than the control group during the same period(P＜0.05);The serum CRP,D-dimer,and FIB of the two groups of patients were significantly lower than that before treatment,while the experimental group was lower than the control group(P＜0.05).Conclusion:The combination of Jupi Banxia Decoction and Tongqiao Huoxue Decoction has a significant therapeutic effect on CSVD.It can significantly improve the daily living abil-ity of patients,alleviate inflammatory reactions,and reduce the formation of microemboli,with high safety.
NETL
NSTL
万方数据
维普
