单侧乳腺癌改良根治术患者采用右美托咪定麻醉的临床价值
Clinical value of dexmedetomidine anesthesia in patients with unilateral breast cancer modified radical mastectomy
姚娟1
作者信息
- 1. 巨野县人民医院,山东 巨野 274900
- 折叠
摘要
目的:明确右美托咪定应用于单侧乳腺癌改良根治术患者临床麻醉的价值.方法:将本院 120 例单侧乳腺癌改良根治术患者采用计算机随机均分为观察组(n =60)和对照组(n =60);观察组在常规麻醉方案基础上应用右美托咪定,对照组应用常规麻醉方案;对两组患者的临床麻醉效果、麻醉苏醒期躁动及血流动力学指标进行比较.结果:两组比较,患者手术时间无统计学差异(P＞0.05),观察组术后(2 h、8 h)镇静Ramsay评分低(P＜0.05),术后清醒时间、拔管时间少(P＜0.05),躁动分级评分、SAS评分低(P＜0.05);麻醉前,两组SBP、DBP、HR、SpO2 数据无统计学差异(P＞0.05);拔管时,观察组SBP、DBP和HR均明显低于后者、SpO2 高于后者(P＜0.05).结论:单侧乳腺癌改良根治术患者采用右美托咪定具有良好的麻醉效果,有助于减少患者麻醉苏醒期躁动,改善血流动力学情况.
Abstract
Objective:To clarify the clinical anesthesia value of dexmedetomidine in patients undergoing unilateral breast cancer modified radical mastectomy.Methods:120 patients undergoing unilateral breast cancer modified radical mastectomy in our hospital were randomly divided into an observation group(n =60)and a control group(n =60)using a computer.The observation group received dexmedetomidine on top of the regular anesthesia protocol,while the control group received the regular anesthesia protocol.The clinical anesthesia effects,postoperative agitation during the recovery period,and hemodynamic indicators were compared between the two groups.Results:There was no statistical difference in the operation duration between the two groups(P＞0.05).The observation group had lower Ramsay sedation scores at 2 h and 8 h post-operation(P＜0.05),shorter postoperative recovery time and extubation time(P＜0.05),lower agitation rating scores and SAS scores(P＜0.05).Before anesthesia,there was no statistical difference in SBP,DBP,HR,and SpO2 data between the two groups(P＞0.05).During extubation,SBP,DBP,and HR in the observation group were significantly lower than those in the control group,while SpO2 was higher(P＜0.05).Conclusion:U-sing dexmedetomidine in patients undergoing unilateral breast cancer modified radical mastectomy has good an-esthesia effects,helping to reduce postoperative agitation during the recovery period and improve hemodynamic conditions.
关键词
右美托咪定/单侧乳腺癌改良根治术/麻醉效果/麻醉苏醒期躁动/血流动力学Key words
Dexmedetomidine/Modified radical mastectomy for unilateral breast cancer/Anesthetic effect/Anesthesia recovery agitation/Hemodynamics引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据