Analysis of the Effect of Sequential Treatment of Pediatric Pneumonia with Antibiotics
Objective:To determine the effect of sequential treatment with antibiotics on pediatric pneu-monia patients.Methods:90 children with pneumonia were evenly divided into a sequential treatment group and a basic group using the blind touch dichroism method;The basic group received azithromycin treatment,while the sequential treatment group received sequential treatment;clinical indicators between two groups were com-pared.Results:The effective rates of the two treatment groups were compared,and the sequential treatment group(97.78%)was higher than the base group(84.44%),with a significant difference between the groups(P＜0.05).The improvement of clinical symptoms in the two groups was compared.The fever disappearance time(3.03±0.79 and 4.52±1.28)d,cough disappearance time(5.22±1.58 and 8.39±2.11)d,pul-monary rales disappearance time(4.35±1.67 and 7.04±2.11)d,shortness of breath disappearance time(4.13±0.84 and 5.68±1.26)d,X-ray shadow disappearance time(18.36±9.42 and 24.39±12.01)d and hospitalization time(6.75±1.37 and 8.52±2.28)d in the sequential group were all less than those in the basic group,the difference between the groups was significant(P＜0.05).The levels of inflammatory fac-tors in the hs-CRP(4.87±1.15 and 11.39±3.21)mg/L,PCT(0.05±0.02 and 0.09±0.04)pg/ml,WBC(3.02±0.85 and 3.87±0.65)×109/L,1 L-6(18.45±4.98 and 22.48±5.06)ng/L and TNF-(25.31±7.06 and 36.94±8.01)mg/L sequential group were lower than those in the basic group,and the difference between the groups was significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:Compared with the use of azithromycin alone,sequential treatment with antibiotics can significantly improve the therapeutic effect in children with pneumonia.
NETL
NSTL
万方数据
维普
