Investigation of the Predictive Value of Early Pregnancy Uterine Artery Pulsatility Index in Combination with Placental Growth Factor and Mean Arterial Pressure for Preeclampsia
Objective:To explore the combined application value of uterine artery pulsatility index(UT-PI)during early pregnancy,placental growth factor(PLGF),and mean arterial pressure(MAP)in predicting preeclampsia(PE)in pregnant women.Methods:This study included 70 pregnant women diagnosed with PE as the research group and 70 healthy pregnant women from the same period as the control group.UTPI,PLGF,and MAP were measured during the early pregnancy phase for both groups.Results:The research group exhibi-ted higher levels of UTPI and MAP during the early pregnancy phase compared to the control group,and a lower PLGF level.Notably,the combined measurement of these three indices significantly improved the sensitivity,accuracy,and specificity for diagnosing PE over individual assessments(P<0.05).Conclusion:The concur-rent evaluation of UTPI,PLGF,and MAP in early pregnancy enhances understanding of the pathophysiological characteristics of PE,facilitating the determination of disease severity and progression trends.This multi-para-metric approach provides a robust basis for clinical diagnosis,differentiation,prevention,and intervention strat-egies in managing PE.
Early Pregnancy Uterine Artery Pulsatility IndexPlacental Growth FactorMean Arterial PressurePreeclampsia
万方数据
维普
