Objective:To investigate the clinical efficacy,safety,and effectiveness of the self-formulated Chaihu-Xiang-fu prescription devised by Professor Li Pei in treating chronic atrophic gastritis(CAG)with liver stagnation,spleen deficiency,and damp-heat syndrome.Methods:A total of 50 patients with CAG(liver stagnation,spleen deficiency,and damp-heat syn-drome)who visited our hospital from May 2021 to October 2022 were selected as the study subjects.They were treated with the Chaihu-Xiangfu prescription with modifications.The traditional Chinese medicine(TCM)syndrome scores,endoscopic findings,histopathological efficacy,safety indicators,and the occurrence of adverse reactions before and after treatment were compared.Results:The total effective rate of treatment was 92％.Endoscopic and pathological evaluations before and after treatment showed significant reductions in chronic inflammation and atrophy scores(P＜0.05).Paired t-tests on TCM syndrome scores before and after treatment revealed significant reductions in epigastric pain,epi-gastric distension,acid regurgitation,belching,and total TCM syndrome scores(P＜0.05),while heartburn did not show significant difference(P＞0.05).No adverse events occurred during medication.Conclusion:The Chaihu-Xiangfu prescription significantly improves symptoms in patients with CAG with liver stagnation,spleen deficiency,and damp-heat syndrome,repairs lesioned gastric mucosa,and is effective and safe for use.
关键词
柴胡香附方/慢性萎缩性胃炎/肝郁脾虚证/湿热证
Key words
Chaihu-Xiangfu prescription/Chronic atrophic gastritis/Liver stagnation and spleen deficiency syndrome/Damp-heat syndrome
维普
万方数据