In the presence of ferrous sulfate mordant,the effects of concentration of dyeing solution,concentration of mordant and dye-ing temperature on K/S value of cotton coarse cloth dyed by Sappan Wood natural dye was investigated based on single factor experi-ment.The Box-Behnken response surface method was used to optimize the dyeing process.The results showed that the optimum process conditions for natural dyeing cotton coarse cloth were as follows:the concentration of dye solution was 82.1 g/L,the concen-tration of mordant was 3.5 g/L and the dyeing temperature was 60℃.The effect order of these factors for cotton coarse cloth was dye concentration>dosage of mordant>dyeing temperature.The dry rubbing color fastness of dyed fabric was 4-5,the wet rubbing color fastness was 3-4,and the overall performance was improved.