The pathogenesis and therapeutic role of exosomes in the progression of allergic diseases
Allergic diseases such as allergic rhinitis(AR),atopic dermatitis(AD)and allergic asthma(AS)are systemic diseases caused by disorders of the immune system.The incidence of these diseases is increasing year by year due to factors such as environmental pollution and climate change,which are of increasing concern.Exosomes are extracellular vesicles that can be released by all cells of the body to transport cargos between cells and assist in intercellular communication.Immune cells can release or use exosomes to enhance,deviate or suppress the immune response,thus exosomes play an important role in the immune response and can be used to mitigate the development of allergic diseases in patients through exosome-related immunotherapy.In this paper,the pathogenic mechanisms of exosomes from different sources in common allergic diseases such as AR,AD and AS and their potential therapeutic roles are being reviewed.
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