Predictive value of EGRIS score combined with CONUT score for the need of mechanical ventilation in Guillain-Barré syndrome
Objective The study aimed to investigate the predictive value of Erasmus GBS respiratory insufficiency score(EGRIS)and controlling nutritional status(CONUT)score for the need of mechanical ventilation in patients with Guillain-Barre syndrome(GBS).Methods A total of 192 patients with GBS admitted to the Affiliated Hospital of Xuzhou Medical University from December 2014 to August 2023 were selected.According to whether mechanical ventilation,they were divided into mechanical ventilation group and non-mechanical ventilation group.The general data and EGRIS score,CONUT score were compared between the two groups.Multivariate logistic regression analysis was used to analyze the risk factors of mechanical ventilation.Receiver operator characteristic(ROC)curve was used to analyze the predictive value of EGRIS score and CONUT score on mechanical ventilation.Results The levels of EGRIS score and CONUT score in mechanical ventilation group were higher than those in non-mechanical ventilation group,the differences were statistically significant(Z=-6.035,-5.778;all P<0.001).Multivariate logistic regression analysis showed EGRIS score and CONUT score were the independent risk factors for the need of mechanical ventilation(P<0.05).The ROC curve showed that the area under the curve of EGRIS score,CONUT score and the combination of the two were 0.856,0.841 and 0.909,respectively;the sensitivities were 88.89%,70.37%and 77.78%,respectively,and the specificities were 67.88%,87.88%and 86.06%,respectively.Conclusion Both EGRIS score and CONUT score had certain predictive value for mechanical ventilation in patients with GBS,but the combination of them was more reliable in the prediction of the risk of mechanical ventilation in patients with GBS.