Follow-up study on clinical characteristics and traditional Chinese medicine syndrome types of patients infected with novel coronavirus in Wuhan Fangcang Hospital
Objective To analyze the clinical characteristics and prognosis of patients with novel coronavirus disease 2019(COVID-19)in the Wuhan Fangcang Hospital and the correlation with traditional Chinese medicine(TCM)syndrome types.Methods A total of 990 cases of COVID-19 patients admitted to the Wuhan Fangcang Hospital in 2020 were included.Relevant clinical data was collected,and a non-interventional online questionnaire follow-up was conducted for one year to observe the outcomes.Results A total of 990 cases were included,of which 277 cases(27.98%)were mild and 713 cases(72.02%)were common.The main clinical manifestations were fever and chills(69.39%),nasal congestion and rhinorrhea(63.03%),itchy and sore throat(58.08%),dry cough(74.44%),and fatigue(71.31%).The distribution of main TCM patterns in the mild type was obstruction of cold-dampness in the lung pattern(75.09%)and dampness-heat accumulated in the lung pattern(24.91%);in the common type,it was stagnation of toxic dampness in the lung pattern(53.58%),cold-dampness obstructing the lung pattern(34.64%),and pestilent toxic substances with dryness pattern(11.78%).Among them,49.19%of patients met the discharge criteria and were discharged from the Fangcang Hospital,while 50.81%of patients did not meet the discharge criteria and were transferred to designated hospitals for further treatment.Only 328 cases(33.13%)completed the one-year follow-up.There were differences among different TCM patterns in terms of outpatient follow-up visits,blood tests,CT scans(c2=10.776,87.820,241.247;all P<0.05),but there were no significant differences in the proportion of rehospitalization,nucleic acid re-positivity among different TCM patterns(c2=8.325,8.325;all P>0.05).Conclusions Patients with different TCM patterns had different outcomes and prognoses.During the Wuhan period,the patients in the Fangcang Hospital were mainly characterized by obstruction of cold-dampness in the lung pattern and stagnation of toxic dampness in the lung pattern,and the two patterns were more prone to disease recurrence.
COVID-19Traditional Chinese medicine patternsObstruction of cold-dampness in the lung
NETL
NSTL
万方数据
