Epidemiological analysis of hand-foot-and-mouth disease in Fuzhou city from 2015 to 2022
Objective To analyze the epidemiological characteristics of hand-foot-and-mouth disease in Fuzhou city from 2015 to 2022,and provide evidence for the prevention and control.Methods The data of hand-foot-and-mouth disease cases with current address in Fuzhou district was collected from the"China information system for disease control and prevention"during 1st January,2015 to 31th December,2022.The data of hand-foot-and-mouth disease such as age,sex,current address,time of onset and occupation was analyzed by descriptive epidemiological methods,and SPSS 26.0 software.Results A total of 78 023 cases of hand-foot-and-mouth disease was reported in Fuzhou from 2015 to 2022.The incidence of hand-foot-and-mouth disease was 260.00/100 000,186.03/100 000,198.64/100 000,218.61/100 000,104.78/100 000,22.70/100 000,63.02/100 000 and 23.11/100 000,respectively.The average annual incidence rate of hand-foot-and-mouth disease was 131.86/100 000 from 2015 to 2022.The incidence rate was decreasing(x2=1 254.792,P＜0.01).The epidemic curve showed as double-peak in summer from May to July and in autumn from September to November.The incidence rates of Cangshan(345.25/100 000),Jin'an(310.14/100 000)and Luoyuan(245.33/100 000)were higher than those in other areas;the differences were statistically significant(x2=2 564.497,P＜0.01).The ratio of men to women was 1.54∶1.Men had the higher morbidity rate than women;the difference was statistically significant(x2=1 185.740,P＜0.01).The age of onset of hand-foot-and-mouth disease was mainly concentrated in the age group less than 5 years old,the rate of which was 92.30％(72 018/78 023).The main occupations were scattered children,nursery children and students,accounting for 74.99％,20.82％and 3.32％,respectively.The rate of the enterovirus 71(EV71)strain(29.37％)was higher than that of the coxsachie virus A16(COX A16)strain(12.30％);Other enteroviruses such as non-EV71 and non-COX A16 accounted for 58.33％.Conclusions The epidemic curve of hand-foot-and-mouth disease showed as double-peak in Fuzhou.Most of the cases occurred in the junction of urban and rural areas.The majority of hand-foot-and-mouth disease cases were male and children under 5 years.So the kindergartens in the junction of urban and rural areas should strengthen the epidemic prevention and control.The vaccination and the prevention knowledge propaganda should be strengthened,which could significantly reduce the incidence of hand-foot-and-mouth disease.
Hand-foot-and-mouth diseaseControl and preventionEpidemiological characteristicsPathogenesis
NETL
NSTL
万方数据
