Research advance on immune escape mechanism in fever with thrombocytopenic syndrome virus infection
Severe fever with thrombocytopenia syndrome(SFTS)is an emerging infectious disease caused by fever with thrombocytopenia syndrome virus(SFTSV),and cases of infection have been monitored in at least 25 provinces in China.Patients with SFTS have a high mortality rate and complex pathogenesis,and immune escape plays an important role in the mass replication and proliferation of viruses,which is closely related to the disease progression and prognosis of patients.This article focuses on the two mechanisms of innate immunity and adaptive immune escape after viral infection,in order to provide a basis for deepening the understanding of the pathogenic mechanism of immune escape and developing targeted treatment methods.
Fever with thrombocytopenia syndromeImmune escapeInterferon inhibitionB cellsT cells
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