Effect of external diaphragmatic pacing stimulation on diaphragmatic function in patients after uniportal video-assisted thoracoscopic surgery
Objective To study whether external diaphragmatic pacing(EDP)can facilitate the swift recovery of diaphragmatic function in patients with lung cancer post-uniportal video-assisted thoracoscopic surgery,thereby enhancing respiratory function and accelerating their postoperative recovery.Methods A total of 121 lung cancer patients hospitalized in the Fifth Affiliated Hospital of Sun Yat-sen University between March and July 2023 were seclected,after excluding 43 cases who did not meet the enrollment criteria and could not be completed,78 cases were finally enrolled and randomly divided into EDP group and control group.Both groups were given routine rehabilitation after operation.The EDP group was given external diaphragmatic pacing stimulation,while the control group was given external diaphragm pacing blank stimulation.The main outcome measures were the ultrasonic parameters of diaphragm in two groups at different time points.The secondary observation indexes were postoperative complications,pain score,drainage volume of pleural effusion and extubation time of thoracic drainage tube.Results There was no significant difference in the ultrasonic parameters of diaphragm,such as diaphragm thickening fraction(DTF),diaphragm thickness at the end of inspiration(DTei)and diaphragm excursion(DE),between the two groups at TO(P＞0.05),suggesting that the diaphragm function of the two groups was similar before operation.Compared with TO time point,the values of DTei and DE in the two groups at T1 decreased significantly,and the differences were statistically significant(DTei:tconrol group=5.337,tEDP group=6.935,DE:tcontrol group=13.494,tEDP group=15.382;all P＜0.001),but there was no statistical difference between the two groups at T1(all P＞0.05).Compared with T1 time point,DTei,DE at T2 time point in the two groups increased significantly,and the differences were statistically significant(DTei:tcobtrol group=2.969,tEDP group=6.247,DE:tcontrol group=4.249,tEDP group=15.006;all P＜0.05).At T2,the DE of EDP group was significantly higher than that of the control group(t=6.746,P＜0.001),while the difference of DTei between the two groups was not statistically significant(P＞0.05).There was no statistical difference in postoperative complications and drainage tube retention time between the two groups(all P＞0.05),but compared with the control group,the VAS score in EDP group decreased significantly after at T2 time point(t=2.629,P＜0.05).Conclusion External diaphragmatic pacing stimulation could significantly improve the early diaphragm mobility in patients after single-port thoracoscopic lung cancer surgery in a short period of time,reduce patients'pain perception,and was beneficial to accelerating the postoperative recovery of lung cancer patients without obvious adverse reactions.
万方数据
维普
