Application of continuous intercostal nerve block combined with parecoxib sodium and patient-controlled intravenous analgesia pump in uniportal video-assisted thoracoscopic surgery for pulmonary nodule resection
Objective To compare the analgesic effects of continuous intercostal nerve block combined with parecoxib sodium(ICNB+P)versus patient-controlled intravenous analgesia pump(PCIA)in patients undergoing uniportal video-assisted thoracoscopic surgery(U-VATS)for pulmonary nodule resection.Methods The data of 100 cases of single-hole thoracoscopic pulmonary nodule resection in the Fifth Affiliated Hospital of Sun Yat-sen University from September to December,2022 were retrospectively analyzed.According to the inclusion and exclusion conditions,93 cases of qualified pulmonary nodule data were included in this study.A total of 51 patients with ICNB+P analgesia were categorized as the ICNB+P group,and 42 patients with PCIA analgesia were categorized as the PCIA group.The postoperative visual analog scale(VAS)pain scores,diaphragmatic mobility,postoperative adverse reactions,and complications were compared between the two groups.Results At 1,6,12,24,36,48 h after operation,the resting VAS scores of ICNB+P group were significantly lower than those of PCIA group(t=-5.782,-2.952,-4.033,-2.369,-2.149,-3.114;all P＜0.05).The number of analgesic remedies in ICNB+P group within 48 hours after operation was significantly less than that in PCIA group(t=-4.185,P＜0.05).The diaphragmatic mobility in ICNB+P group was significantly higher than that in PCIA group 24 hours after operation(t=2.345,P＜0.05).The difference and change rate of diaphragmatic mobility in ICNB+P group 24 hours after operation were significantly lower than that in PCIA group(t=-3.097,-3.550;all P＜0.05).No nausea,vomiting,dizziness and allergy were found in ICNB+P group,and the incidence of dizziness was significantly lower than that in PCIA group(x2=4.290,P＜0.05).The incidence of pneumonia in ICNB+P group was lower than that in PCIA group with statistical significance(x2=4.019,P＜0.05).Conclusions ICNB+P had better analgesic effect than PCIA after U-VATS surgery,could reduce the number of analgesic rescue times,had lower incidence of side effects and complications,was more conducive to restoring respiratory movement,and improves the quality of postoperative recovery.It had good clinical promotion value.
万方数据
维普
