Analysis of influencing factors and anti-infective drugs in children with Mycoplasma pneumoniae pneumonia complicated by mixed infections
Objective To explore the influencing factors and anti-infective medication situation of Mycoplasma pneumoniae pneumonia(MPP)complicated with mixed infections in children,and provide a basis for the diagnosis and treatment of MPP complicated with mixed infections.Methods A retrospective study was conducted on 90 children with MPP in the inpatient medical record management system of the Ningguo People's Hospital from October 2022 to October 2023.According to the infection status,they were divided into Group A(simple MPP infection children,n=45)and Group B(mixed infection children,n=45).Clinical data of the enrolled children were collected through inpatient and outpatient medical records,and analysis the general situation of the children.The use and adverse reaction of anti-infective drugs in two groups of pediatric patients were analyzed.Results The univariate analysis of MPP complicated with mixed infections in children showed that the cough time,hospital stay,and serum white blood cell(WBC),C-reactive protein(CRP),lactic dehydrogenase(LDH),and neutrophil to lymphocyte ratio(NLR)levels in Group B were significantly higher than those in Group A(t=-3.038,-6.415,-4.423,-3.794,-4.881,-2.488;all P＜0.05).In both groups of anti-infective drug treatment plans,antibacterial therapy was the main treatment,and the number of children in Group B who received ceftriaxone sodium injection and erythromycin injection in combination was significantly higher than that in Group A(x2=7.911,P=0.005),and there was no statistically significant difference in adverse reactions between two groups(P＞0.05).Conclusions It was relatively difficult to treat children with MPP and concurrent mixed infections.Patients with a high suspicion of concurrent mixed infections should receive combined anti-infection treatment,and close attention to drug safety.
万方数据
维普
