Risk factors for sepsis cardiomyopathy in tumor patients
Objective To analyze the risk factors for septic cardiomyopathy(SC)in tumor patients,in order to provide guidance for the clinical intervention of such patients.Methods A total of 180 tumor patients with sepsis admitted to the Cancer Hospital Affiliated to Xinjiang Medical University from January 2020 to January 2023 were selected and divided into SC group(n=73)and non-SC group(n=107)according to whether or not SC occurred.General information,ICU admission scores,vital signs,maximum body temperature,and laboratory examination indicators were compared between the two groups of patients.Multivariate logistic regression model was used to analyze the independent risk factors for SC in sepsis patients.Results The average age,male gender rate,intubation rate,abdominal infection rate,sequential organ failure assessment(SOFA)score,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score,the highest body temperature,serum creatinine(Scr),procalcitonin(PCT),N-terminal pro brain natriuretic peptide(NT-proBNP),cardiac troponin T(cTnT),lactate dehydrogenase(LDH),creatine kinase(CK),creatine kinase isozyme(CK-MB)in the SC group were significantly higher than those in the non-SC group(j/t/Z=2.103,4.242,9.280,4.064,5.886,8.111,6.363,6.882,-2.370,20.442,-10.762,13.041,18.079,-3.264;all P＜0.05).Multivariate logistic regression analysis showed that age and APACHE Ⅱ score were independent risk factors for the occurrence of SC disease in tumor patients(OR=1.070,1.525;both P＜0.05).Conclusion Age and APACHE Ⅱ score were the independent risk factors for the occurrence of SC in tumor patients.
万方数据
维普
