Epidemiological investigation and analysis of the first imported case of kala-azar in Shenzhen
Objective To investigate the origin of the first imported case of kala-azar in Shenzhen,and provide scientific basis for the prevention and control of kala-azar.Methods On March 15,2023,a case of kala-azar was reported in Shenzhen.Clinical data and epidemiological investigations were collected and analyzed for this case based on the relevant literature content.Results The patient,male,75 years old,had arrived in Shenzhen on March 6,2023 and presented with discomfort.According to the clinical manifestations of irregular fever,chills,and decreased peripheral blood cells in this case,the bone marrow smear showed Leishman-Donovan bodies,and the pathogen-targeted sequencing results indicated a high degree of homology with Leishmania donovani.Laboratory test results also include the patient's history of residence in the Taihang Mountains epidemic area in Linzhou city,Anyang,Henan(September 7-October 27,2022).Additionally,the positive screening rate for kala-azar in dogs in this epidemic area was 22.22％.Based on these findings,this case was a confirmed case of kala-azar imported into Linzhou city.Conclusion Combined with the living environment and epidemic situation of the reported cases in Shenzhen,the possibility of infection in Shenzhen was excluded,and it was speculated that the risk of infection in Linzhou city,Anyang,Henan was presumed to be higher.
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