Analysis of the results of 1 196 HIV antibody confirmatory test cases in Xuzhou city,2021-2023
Objective To analyze the results of HIV antibody confirmatory tests in Xuzhou city from 2021-2023,and provide a scientific basis for AIDS prevention and treatment.Method From 2021 to 2023,all HIV samples sent for testing by various AIDS screening laboratories and testing sites in Xuzhou city,as well as those received by the voluntary counseling and testing(VCT)clinic of Xuzhou Center for Disease Control and Prevention,a total of 1 196 samples were reactive after initial screening,and the confirmatory HIV confirmatory experiment was carried out by Western blot method,and the confirmatory test results,demographic characteristics,band type,and the band type information of the confirmed specimens after follow-up were summarized for statistical analysis.Results Among 1 196 confirmed HIV cases,1 123 were positive,59 were indeterminate and 14 were negative in the Western blot screening.The confirmed positivity rates in 2021-2023 were 95.49％,93.22％and 92.86％,respectively,with statistically significant differences in the distribution of confirmed results between years(x2=2 966.080,P＜0.05).There were 952 males and 171 females among the positive cases,with the highest number of cases in the 21-＜41 age group(46.57％)and the predominance of married individuals(54.76％).The highest confirmed positive rate was 96.77％in CDC facilities,followed by 93.13％in medical facilities,and the lowest was 81.58％in blood collection and supply facilities;the differences in confirmed positive rates between different sending facilities were statistically significant in 2021-2023(P＜0.05),and the differences in confirmed positive rates between different sending facilities were statistically significant in the same year(all P＜0.05).The confirmed HIV antibody bands were mainly gp160,gp120,p24 and gp41,with detection rates of 100.00％,100.00％,97.68％and 97.06％,respectively;the differences in detection rates of gp160,gp120,p31 and p1 7 bands between different populations were statistically significant(all P＜0.05).Among the 50 samples that were successfully followed up,the gp160 combination bands all turned positive.Conclusion Male married young adults were still the key group for AIDS prevention and control in Xuzhou city,and the use of nucleic acid testing for indeterminate cases should be a key strategy to shorten the detection window period and achieve early diagnosis.
万方数据
维普
