Bacterial resistance from the perspective of One Health
Antimicrobial resistance has emerged as a global public health hazard,posing threats to human health,animal husbandry and veterinary medicine,as well as environmental safety.Drug-resistant genes,which give rise to bacterial resistance,can disseminate among various species of bacteria via horizontal gene transfer,facilitated by mobile genetic elements such as plasmids,transposons and integrons.Consequently,this exacerbate the risks to public health.Considering the extensive distribution of drug-resistant bacteria across various niches and the prevalent presence of drug-resistant genes in diverse bacterial species,there is a global consensus on implementing the One Health approach to monitor and manage the epidemics of drug-resistant bacteria.From a One Health perspective,this paper reviews the research progress of bacterial drug resistance mechanism,the spread of drug resistance genes and the detection technologies of drug resistance,and provide some theoretical basis for curbing antimicrobial resistance crisis and safeguarding the common health of"human-animal-environment".
Antibacterial drugBacterial drug resistanceMobile genetic elementsOne HealthDrug resistance detection technology
万方数据
维普
