With the breakthrough in intelligent technology,the development of artificial intelligence has entered a high-level development stage.The deep integration of strong artificial intelligence and education promotes the development of personalized education.At the same time,strong artificial intelligence enabling personalized education faces many challenges,such as the education standardization has been strengthened,the conflict between soft collaboration and hard collaboration in human-machine collaboration,the lack of humanistic value caused by comprehensive control of tool rationality,knowledge bias brought by technological Leviathan,and the"intelligent gap"enhancing educational inequality.Therefore,this paper researched the theory and practice of strong artificial intelligence enabling personalized educa-tion,to enhance the digital literacy of teachers and students,emphasize innovative research oriented educational concepts,use intelligent de-vices to record data,formulate personalized cultivation plans,promote the autonomous personalized learning mode of"machine tutored—teacher guided",pay more attention to multiple evaluations,optimize emotional value algorithms to promote personalized"human machine"interaction,continuously promote interdisciplinary education and enhance personalized practical teaching.