A study on the method of evaluating the efficacy of a firming cosmetic
By evaluating the efficacy of a cosmetics with palmitoyl pentapeptide-4 as the main functional ingredient,the study establishes a clinical evaluation method system for firming efficacy.Thirty-one female subjects aged 20-50 were screened,and the skin indexes including the objective test data,image methods and subject self-assessment methods were evaluated after using the product for 0 week,4 weeks and 8 weeks,respectively.The parameters of skin elasticity and skin dermal density in the cheeks and canthus of the subjects,as well as the TPEF images and the SHG images,were captured,and comparative analyses were carried out.The results show significant changes in skin elasticity,dermal density(P<0.001)and DEJI(P<0.01)after 8 weeks,which are consistent with the results of the subjects'self-ratings,indicating a correlation between the methods.This research can provide technical supports for the establishment of a cosmetic firming efficacy evaluation method system.
elasticityfirmnesstwo-photon imaging technologyultrasoundevaluation of cosmetic efficacyelastin fibrescollagen fibres
国家科技期刊平台
NSTL
万方数据
维普
