首页|药用层孔菌发酵液控油及收缩毛孔机理及功效研究

药用层孔菌发酵液控油及收缩毛孔机理及功效研究

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将药用层孔菌和乳酸菌进行双向发酵得到药用层孔菌发酵液,检测药用层孔菌发酵液和药用层孔菌水提液的活性成分含量,从分子、细胞、动物和人体等方面研究药用层孔菌发酵液在控油和收缩毛孔等方面的功效作用,结果表明,药用层孔菌发酵液具有更高的活性成分含量、可以减少ABTS自由基的生成、抑制炎症因子TNF-α和IL-6的表达、调控5α还原酶活性、减少皮肤油脂分泌、促进Ⅰ型胶原蛋白(COL-Ⅰ)的表达、抑制金属蛋白酶-1(MMP-1)表达、具有收缩毛孔的趋势,具备成为具有控油和收缩毛孔功效的化妆品原料的潜力.
Study on the mechanism and efficacy of controlling oil and shrinking pores in fermentation broth of Fomes officinalis
The fermentation broth of Fomes officinalis was obtained by two-way fermentation of Fomes officinalis and Lactococcus lactis,and the contents of active components in the fermentation broth and aqueous extract were detected.The effects of Fomes officinalis fermentation broth on oil control and pore contraction were studied from the aspects of molecule,cell,animal and human body.The fermentation of Fomes officinalis has higher content of active components,can reduce the production of ABTS free radicals,inhibit the expression of inflammatory factors TNF-α and IL-6,regulate the activity of 5α reductase,reduce skin oil secretion,promote the expression of type Ⅰ collagen(COL-Ⅰ),inhibit the expression of metalloproteinase-1(MMP-1),have the tendency of shrinking pores.It has the potential to become a cosmetic raw material with the effect of oil control and pore refining.

Fomes officinalisraw material of cosmeticsfermentation technologyoil control effectshrinking pores

宋阳、吕永博、任晗堃、彭娇龙

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太和康美(北京)中医研究院有限公司,北京 102401

北京东方淼森生物科技有限公司,北京 101200

药用层孔菌 化妆品原料 发酵技术 控油功效 收缩毛孔

2024

日用化学工业(中英文)
中国日用化学工业研究院

日用化学工业(中英文)

CSTPCD北大核心
影响因子:0.553
ISSN:1001-1803
年,卷(期):2024.54(5)
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