Multi-photon imaging technology and its application in cosmetic evaluation
Multi-photon imaging technology is an optical imaging method that has been used to observe the structure of human skin tissue,which is based on the near-infrared lasers at different wavelengths.Endogenous fluorescent components in specific skin tissues or exogenous fluoresce-labeled substances can emit different fluorescence excited by the light,thereby observing and distinguishing specific tissue structures in different skin layers.In recent years,multi-photon imaging technology has gradually been applied to cosmetic evaluation,such as evaluating the effects of cosmetics on anti-wrinkle,whitening,spot removing and skin penetration.It can evaluate the effect of anti-wrinkle by monitoring the changes of skin metabolism or morphology,classify the specific skin type,evaluate the efficacy of cosmetics whitening ingredients by quantifying the distribution and content of melanin,and visualize the process of skin penetration of cosmetic ingredients.The objective and visual images have broad prospects which can provide quantitative results.This review summarizes the application and progress of this in vivo,non-invasive and accurate three-dimensional method in cosmetic evaluation.
Multi-photon imaging technologycosmetic evaluationanti-wrinklewhitening and spot removingskin penetration
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