The anti-aging potential of peptides from fermented Nannochloropsis sp.
The extraction and composition analysis of peptides(FNPs)from fermentation Nannochloropsis sp.,as well as their anti-aging effects on Drosophila melanogaster in vivo were investigated.Compared with the non-fermentation group,the number of peptide in FNPs increases by about 100,and the oxidation sites in the peptides also increase.The maximum absorption intensity of FNPs is observed at 258 nm with a dose-dependent relationship.Compared with the control group,5 μg/mL FNPs extends the mean life span of the the natural aging Drosophila melanogaster for 13 days.Additionally,for 70-90 days old,the deterioration of oxidative stress indicators such as MDA,SOD,and CAT caused by age are significantly restored and increased to the level of positive group by FNPs at 0.5 and 5 μg/mL.These results indicate that FNPs have potential as a promising nutritional component for alleviating human health problems induced by aging.It can also be used as a new antioxidant ingredient for functional food development or cosmeceutical applications from a resource rich and easily obtainable raw material Nannochloropsis sp..
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