首页|云防风提取物的美白与抗氧化功效研究

云防风提取物的美白与抗氧化功效研究

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为研究不同溶剂提取的云防风提取物的美白和抗氧化功效,进行了B16细胞内酪氨酸酶活性和黑色素合成、多种自由基清除实验.实验结果表明,云防风提取物(水层)0.03 mg/mL对细胞内酪氨酸酶活性具有显著抑制效果,0.03,0.15,0.3 mg/mL对黑色素合成均具有一定抑制作用,但抗氧化能力弱.云防风提取物(石油醚层)0.01、0.05 mg/mL对细胞内酪氨酸酶活性具有抑制效果,0.1 mg/mL对黑色素合成具有显著的抑制作用,但在抗氧化能力方面相对很弱.由上述结果可知,云防风提取物有美白功效,在开发化妆品天然植物美白活性成分上具有一定的开发价值.
Study on the whitening and antioxidant effects of Saposhnikovia divaricata extract
To study the skin-whitening and antioxidant effects of Saposhnikovia divaricata extract extracted with different solvents,experiments were conducted on the tyrosinase activity and melanin synthesis in B16 cells,as well as the scavenging ability of various free radicals.The experimental results showed that Saposhnikovia divaricata extract(aqueous layer)at a concentration of 0.03 mg/mL had a significant inhibitory effect on intracellular tyrosinase activity,and the concentrations of 0.03,0.15,and 0.3 mg/mL all exhibited certain inhibitory effects on melanin synthesis,but its antioxidant capacity was weak.Saposhnikovia divaricata extract(petroleum ether layer)at the concentrations of 0.01 and 0.05 mg/mL inhibited intracellular tyrosinase activity,and a concentration of 0.1 mg/mL had a significant inhibitory effect on melanin synthesis,but it did not demonstrate good antioxidant effects.From the above results,it can be concluded that Saposhnikovia divaricata extract has skin-whitening properties and holds a certain development value in the development of natural plant-based skin-whitening active ingredients for cosmetics.

Saposhnikovia divaricatawhiteningmelanintyrosinaseantioxidation

陈秦君、刘娟

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云南白药集团上海科技有限公司,上海 201107

云南白药集团有限公司,云南 昆明 650500

云防风 美白 黑色素 酪氨酸酶 抗氧化

2025

日用化学品科学
中国日用化学工业信息中心

日用化学品科学

影响因子:0.26
ISSN:1006-7264
年,卷(期):2025.48(1)