Optimization of a Method for the Detection of 1,2-Propanediol in Infant Formula
According to the first method for the determination of 1,2-propanediol in foods specified by the national food safety standard GB 5009.251-2016,1,2-propanediol was extracted from milk powder using acetonitrile and was detected using a gas chromatograph(GC).Extraction solvent and standing time were investigated by one-factor-at-a-time method.Furthermore,response surface methodology(RSM)was employed to optimize oscillation time and standing time based on 1,2-propanediol recovery.The optimum extraction conditions were determined as acetonitrile,4 ℃,94-102 s and 1.2-1.4 h for extraction solvent,standing temperature,oscillation time and standing time,respectively.Under these conditions,the spiked recovery range of 1,2-propanediol was 95.2％-99.8％.The coefficient of variation for repeatability of the method was 1.62％,and it had good selectivity.The optimized method is suitable for the determination of 1,2-propanediol in milk powder.
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