Advances in the Sex Determination Mechanisms of Amphibians
Two heterogametic types (XX/XY and ZZ/ZW) for genetic sex determination are present within families or genera of amphibians,and even in different geographic populations of one species.This phylogenetic distribution suggests the transitions between the two heterogametic types may frequently occur in this lineage.Homomorphic sex chromosome is prevalent in amphibian,and both "high-turnover" and "fountain-of-youth" hypotheses may explain this phenomenon.Steroids are the key factors for sex determination during the early stage of sexual development.Additionally,the recently identified DM-W gene,was introduced as the only known sex determination gene in amphibian.This brief review would contribute to understand the origin and evolution of sex determination mechanisms of amphibians,to protect the wild population of endangered amphibian,and to make better use of those aquatic amphibian species.
amphibiansex-determination systemhomomorphic sex chromosomesex determination gene