Investigation of Antibiotic Residues and Analysis of Bacterial Resistance in 16 Large Poultry Farms in Sichuan Province
To evaluate the presence of antibiotic residues and bacterial resistance in poultry farm manure,the characteris-tics of antibiotic residues and Enterobacteriaceae antibiotic resistance in the poultry manure samples from 16 large-scale poultry farms in Sichuan Province were studied,and the level of antimicrobial resistance selection(RQAMR)was evaluated also.The results showed that 18 kinds of antibiotics with concentrations ranging from 0.54 to 2 780.00 μg·kg-1 were de-tected from 16 manure samples.The residual status of sulfonamides,tetracyclines,chloramphenicols,and quinolones in livestock were relatively serious.The faeces from ZJZX farm had the highest concentration of doxycycline,which reached 2 780.00 μg·kg-1.The RQAMR ranged from 0.004 0 to 10 561.13,indicating a high risk of selective antibiotic re-sistance.Moreover,14 strains of multidrug resistant Enterobacteriaceae bacteria were isolated and identified in the manure samples,and 33 different antibiotic resistance genes were detected.It is recommended that the relevant departments should strengthen the control of antibiotics such as doxycycline,flufenicol,and enrofloxacin and improve the monitoring of Enterobacteriaceae antibiotic resistance in livestock and poultry breeding enterprises.
NETL
NSTL
万方数据
维普
