基于急性生理与慢性健康状况评分系统Ⅱ的预见性干预模式在重症脓毒症患者治疗中的应用
Effect of Predictive Intervention Model Based on Acute Physiology and Chronic Health Evaluation Ⅱ in the Treatment of Patients with Severe Sepsis
代晓 1邢妍妍 1郭东玲 2李晓娟3
作者信息
- 1. 河南中医药大学人民医院,郑州人民医院重症医学科,郑州 450003
- 2. 河南中医药大学人民医院,郑州人民医院感染预防与控制办公室,郑州 450003
- 3. 河南中医药大学人民医院,郑州人民医院心脏大血管外科,郑州 450003
- 折叠
摘要
目的:探讨急性生理与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分的预见性干预模式对重症脓毒症患者治疗指标的影响.方法:选取 2022 年 1 月至2023 年5 月本院收治的92 例重症脓毒症患者作为研究对象.依据干预模式,将其分为研究组(n=46,给予基于APACHEⅡ评分的预见性干预)和对照组(n=46,给予常规干预).比较两组患者各项治疗指标.结果:研究组患者机械通气时间、抗菌药物使用时间、ICU住院时间短于对照组,住院费用比低于对照组,差异均有统计学意义(P＜0.05);研究组患者干预 6h后,中心静脉压、平均动脉压、中心静脉血氧浓度(ScvO2)、动脉血氧分压(PaO2)、PaO2与吸入氧分数(FiO2)的比率(PaO2/FiO2)值高于对照组,心率均低于对照组,差异均有统计学意义(P＜0.05);两组患者并发症发生率比较,差异无统计学意义(P＞0.05).结论:基于APACHEⅡ评分的预见性干预模式可有效改善重症脓毒症患者的相关治疗指标,值得临床推广.
Abstract
Objective:To explore the effect of predictive intervention model based on acute physiology and chronic health evaluationⅡ(APACHEⅡ)scores on treatment indicators of patients with severe sepsis.Methods:A total of 92 patients with severe sepsis admitted to our hospital from January 2022 to May 2023 were selected in this study.According to intervention model,they were divided into study group(n=46,received predictive intervention based on APACHEⅡscore)and control group(n=46,received routine intervention).The treatment indicators of patients with severe sepsis were compared between the two groups.Results:The mechanical ventilation time,antibiotic use time and ICU stay time of the study group were shorter than those of control group,and the hospitalization cost was less than that of control group,the differences were statistically significant(P<0.05).After 6 hours of intervention,the central venous pressure,mean arterial pressure,systemic central venous oxygen saturation(ScvO2),arterial partial pressure of oxygen(PaO2)and PaO2/FiO2 values of study group were higher than those of control group,and the heart rate was lower than that of control group,the differences were statistically significant(P<0.05).There was no significant difference in incidence of complications between the two groups(P>0.05).Conclusion:The anticipatory intervention model based on APACHE Ⅱ score can effectively improve the relevant therapeutic indexes of patients with severe sepsis and is applicable for clinical popularization.
关键词
APACHEⅡ评分/预见性干预/重症脓毒症/治疗Key words
Acute Physiological and Chronic Health Status Scoring System Ⅱ/Anticipatory intervention/Severe sepsis/Treatment引用本文复制引用
出版年
2024
NETL
NSTL
万方数据