脓毒症患者中肺炎克雷伯菌的分布及耐药情况研究
Study on Distribution and Drug Resistance of Klebsiella Pneumoniae in Patients with Sepsis
柳婉琼 1杨培源1
作者信息
- 1. 襄城县人民医院检验科,许昌 461700
- 折叠
摘要
目的:探讨在耐药肺炎克雷伯菌脓毒症患者中肺炎克雷伯菌的分布及耐药情况.方法:选取 2022 年 1 月至 2023 年 7 月期间本院收治的 80 例脓毒症患者为研究对象,患者均予以实验室相关指标检测,分析其病原菌分布与构成情况.结果:80 例脓毒症患者合计有 190 株病原体,其中革兰阴性菌株最多,肺炎克雷伯菌占 12.63%,并且药敏试验结果显示肺炎克雷伯菌仅对头孢唑林、头孢呋辛、头孢他啶、头孢曲松、氨曲南这 5 种药物的耐药率超过45%.结论:对于脓毒症患者,诊疗过程中应该重视实验室微生物检测数据,加强耐药肺炎克雷伯菌耐药状况监控,可以更好地进行针对性治疗以及预后评估.
Abstract
Objective:To explore the distribution and drug resistance of Klebsiella pneumoniae in patients with sepsis.Methods:A total of 80 patients with sepsis admitted to our hospital from January 2022 to July 2023 were selected as the research objects,and all of them were tested with relevant laboratory indicators to analyze the distribution and composition of pathogenic bacteria.Results:There were 190 strains of pathogens in the 80 patients with sepsis,among which gram-negative strains were the most common,while Klebsiella pneumoniae accounted for 12.63%,and the drug susceptibility test results showed that the resistance rate of Klebsiella pneumoniae to five drugs:cefazolin,cefuroxime,ceftazidme,ceftriaxone and amtronam was over 45%.Conclusion:For sepsis patients,paying attention to laboratory microbial detection and strengthening monitoring drug resistance of resistant Klebsiella pneumoniae during diagnosis and treatment can effectively control the development of patients'disease.
关键词
微生物检验/耐药肺炎克雷伯菌/脓毒症/诊断/预后评估Key words
Microbiological test/Drug-resistant Klebsiella pneumoniae/Sepsis/Diagnosis/Prognosis assessment引用本文复制引用
出版年
2024
NETL
NSTL
万方数据