The Progress and Challenges in Computational Simulation of Calciumphosphorus-based Bioceramics
Calciumphosphorus-based(CaP)bioceramic materials demonstrate significant potential in the biomedical field,particu-larly for bone repair and replacement.Traditional experimental methods are often constrained by long durations,high costs,and strin-gent conditions.The introduction of computational simulation technology plays a crucial role in understanding and optimizing the per-formance of CaP bioceramic materials.The progress in the computational simulation of CaP bioceramic materials is reviewed in this pa-per,drawing on both domestic and international research as well as recent work from our group.The numerous challenges currently faced in this area are highlighted.Finally,the future development of this field is anticipated,and the importance of advanced computa-tional methods combined with experimental verification is emphasized.This is expected to further promote the application and develop-ment of CaP bioceramic materials in biomedicine.